No, it's something more related to the terms 'stir crazy' or 'cabin fever.' Which basically result from isolation in confined quarters. Which includes things like a strong desire to get out of said confined quarters, and go outside; even if doing so isn't possible. And even going out into space may not be enough; after all, you're still confined to wearing a movement-constricting space-suit and such to protect you from exposure to the outside.
Though privacy is its own issue; which would also be problematic on long trips. Barring vast advances in spacecraft tech, you want it to be as small as possible, with a crew of at least several individuals (largely for socialization issues; being completely isolated would put you off the deep end quicker than a meeting with a Shub-Niggurath), which means really tight spaces in which you are stuck with the same people, possibly for years.
There are other possibilities in terms of expanding the social horizons of such things. The ISS, for example, recently acquired Kirobo, a small humanoid robot with natural language processing software, meant as an experiment in robotic companions for long journeys. In general, humans (
and chimps too, apparently), respond quite well to robots for social stimulation. And in general, any psychological problems brought about 'isolation' are actually brought about by
perceived isolation, and so can be solved by introducing artificial companions just as easily as real ones. Which is a good deal easier than adding life support for more people.