The syndrome system would work just fine for handling the symptoms of a disease, but the transmission part is a bit more difficult, as ideally it would happen among both civ-pop and histfigs.
Diseases will need their own raws that describe how they interact with non-historical population and what syndrome it results in should it come in contact with a historical figure. Syndromes themselves will also need to be retooled to allow them to be transmittable in various ways.
Infection Mode
aka. "Pandemic: Dwarf Fortress Edition" when?
I want a disease that turns dwarves into mushrooms.
better yet, plump helmet men
Here.
[INTERACTION:MUSHROOM]
[I_TARGET:A:CREATURE]
[IT_LOCATION:CONTEXT_CREATURE]
[IT_FORBIDDEN:NOT_LIVING]
[IT_AFFECTED_CLASS:GENERAL_POISON]
[IT_MANUAL_INPUT:creatures]
[I_EFFECT:ADD_SYNDROME]
[IE_TARGET:A]
[IE_IMMEDIATE]
[SYNDROME]
[SYN_NAME:fungus]
[SYN_AFFECTED_CLASS:GENERAL_POISON]
[CE_FEVER:SEV:250:PROB:100:START:250:PEAK:1500:END:25000]
[CE_BLISTERS:SEV:325:PROB:100:BP:BY_CATEGORY:ALL:SKIN:START:250:PEAK:1500:END:25000]
[CE_BODY_TRANSFORMATION:START:22500]
[CE:CREATURE:PLUMP_HELMET_MAN:MALE]
[CE_CAN_DO_INTERACTION:START:1500:END:25000]
[CDI:ADV_NAME:Spread the plague]
[CDI:INTERACTION:MUSHROOM]
[CDI:TARGET:A:LINE_OF_SIGHT]
[CDI:TARGET_RANGE:A:10]
[CDI:WAIT_PERIOD:30]