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Messages - Trekkin

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121
General Discussion / Re: AmeriPol thread
« on: December 17, 2019, 11:48:59 pm »
The "according to him" running through that is the major methodological problem here, and the one exacerbated by his rush to present. If he has proof that half those corrections fall out of place, that would itself be publishable. If he has new metrics for quantifying orthodontic effectiveness, the same thing would apply. Neither of us could find anything published to that effect.

In the absence of that, putting any of this where the public can find it just invites people to skip all the fiddly steps in figuring out if it works or how it works or why it works or when it doesn't work and just do it without anyone knowing how to check whether what they're doing is right. We need at least a validated mechanistic explanation to start that process.

See, without some way to plug what we want to test into science on a mechanistic level, what he's proposing isn't so different from the folks who used to strap weasel balls to their thighs as a contraceptive or bleed people to make them feel better; if we don't know how it's supposed to work, we don't know how to test what's actually working, if anything, and no amount of anecdote can get us to that mechanistic hypothesis.

We both looked for the things that would let me do something other than dismiss this out of hand. Neither of us found them. In light of that, what he has done is spectacularly irresponsible.

122
General Discussion / Re: AmeriPol thread
« on: December 17, 2019, 09:27:19 pm »
Yeah, because it didn't. He got where he got, and then he stopped doing real medicine. This sort of thing is part of why dentistry and especially orthodontics is the mess that it is: because we don't vet proposed procedures with enough rigor. The solution is not to welcome more insufficiently-researched pseudomedicine. The solution is to actually do the longitudinal studies required to establish how to predict long-term outcomes and set standards of care based on that as we refine our understanding, and keep doing that continuously.

As to your larger point, you're absolutely right: it's absolutely a reflexive dismissal, because that's required of scientific inquiry. It's part of the fundamental tradeoff surrounding the practice of science: findings can be helpful even if they're wrong so long as we follow correct procedure, but they're worthless even if they're right unless and until we do. We can't do anything with them; there's necessary metadata for us to integrate new information into our existing understanding in a rigorous way that anecdotes just don't have. The rest of the process from grants to publications is built on that, and with good reason: this is the best tool we have to believe as many true things and as few false things as possible, but it's very fragile and hard to tell when it breaks.

If I had come across this idea on a review board or something as a theoretical possibility, I'd certainly be skeptical, but it'd have the necessary surrounding information for the proposal to be evaluable on its merits, and I certainly wouldn't be dismissive. (I'd also be deeply confused as to why it got handed to a computational biologist for review, but it's not impossible.) It's like the difference between the statements "pi is less than two" and "pi is green." The first one is wrong, and we can prove it. The second one is pointless because we can't; the only possible answer is "come back when you have something scientific."  Going before the public and saying "maybe pi is green, I don't know, I'm just asking questions" is not something anyone with any credibility should do.

123
General Discussion / Re: AmeriPol thread
« on: December 17, 2019, 08:37:06 pm »
I have more respect for that attempt that someone shitting on something that literally cannot cause harm, simply for the egotistical benefits of doing so.

There's inherent harm in putting the imprimatur of medicine on that which is not scientific, because then it makes it easier for people to go point to it later and say "well, a doctor said that, too. pfft, doctors, am I right?" and take laetril instead of chemotherapy drugs or avoid vaccinations or something. People don't need a good reason to do the easy alternative to something hard or unpleasant, even if it doesn't work. They just need an excuse. Every time we give them that excuse, we effectively make real medicine harder on a societal scale.

124
General Discussion / Re: AmeriPol thread
« on: December 17, 2019, 08:00:25 pm »
Yeah, it's a fairly classic conspiracy theory -- and, with apologies to smjjames for the slight derail, it's illustrative of why conspiracies of this type work and how they embed themselves into politics, so as a case study in modern American political dysfunction it has some merit here.

At the core of every conspiracy theory there's a gap, if you will, a hole in the shape of a demonstrably probative data set that would demonstrate the falsifiable claims of the conspiracy to be true and that no one in the conspiracy actually has. The rest of the conspiracy canon consists of a series of tactics to encourage you to ignore, dismiss, or minimize any concerns about that lack of data. As seen here, generating a narrative about how persecuted the theorists are is an extremely common way to combine forbidden fruit with an entertaining story. You want to know What They Don't Want You to Know, and everyone loves a good underdog story, so hey, two birds with one stone. It also has the effect of encouraging you to identify with the conspiracy and the conspirators simply by listening to them. You are, after all, one of the insiders now, and all the sheeple just don't know what you know. So, how valuable would you prefer to believe this knowledge is -- and by extension, how much better than the sheeple you are for knowing it to be true? And thus does it become more preferable to believe, and the belief that all contrary evidence is fake naturally follows.

In reality, this sort of claim -- cheap, probably harmless, and simple -- is well within the wheelhouse and budget of a number of government-funded science initiatives across the country. A grant for this would be really easy to sell, too, just on a public health basis, and the tricks to get something like this through an IRB aren't hard. Sure, he can't charge for it, but how much better if he could compensate them, like in a proper study? He could even pay himself a salary for it out of the grant, including just for analyzing the dental X-rays. Then he could write a real paper, stick it in a proper peer-reviewed journal, and actually have accomplished something worthwhile. That is not hard for anyone with any business claiming to know anything about medicine.

Instead, he's done the standard pseudoscience end-around run and presented anecdotal "findings" to the public without putting them through peer review. That's really dangerous; every time we let a doctor present unreviewed bullshit to the public, we make it easier for them to ignore real medical and scientific expertise, and people suffer for it. It is also possible, as Mew has demonstrated, to put together enough of a scientific facade to fool laypeople without a shred of real proof, and sucker a lot of people into trying a lot of unhelpful things. Loudly and utterly destroying the career and credibility of mistakes like him is not only just, it is literally the least we can do if we want science to have any meaning at all.

it's basically broscience of health. But the idea that little shit you do or don't do adds up over time is a fundamental rule of life. And stating that seems like a weird thing to try and revoke someone's license over.

No, peddling broscience is a totally valid thing to destroy a man's career over, because how the little shit adds up matters immensely.

125
General Discussion / Re: AmeriPol thread
« on: December 17, 2019, 06:03:13 pm »
Anyhow, back to politics? Though I guess it's tangentially related because healthcare.

It's also got all the hallmarks of a conspiracy theory, which is what American politics runs on now. We've got:

1. A bunch of greedy corporate doctors (Who I can only assume collectively constitute "Big Jaw") suppressing the lone heroic voice of medical genius because money and evil and so forth.
2. Youtube.
3. "Even if it doesn't work, at least it's not expensive"
4. A clear implication that if it doesn't make sense to you, there must be something wrong with you.
5. Irrelevant but touching details as an invitation to engage in special pleading.
6. Things that read a lot like relevant scientific articles but are either not peer-reviewed or not specifically addressing whether the thing works. Sloppy science, in other words.
7. No actual evidence.


126
How is that better than just shaking the whole thing, though, particularly when you may well have dice piled on top of each other?

127
somebody needs to invent a pop-o-matic-bubble that you can open and insert whatever number or kind of dice into.

 I've seen videos of people that surgically extracted the one from a Trouble!(tm) board game, but fitting the correct numbers and types of dice inside for each situation is not really doable with that solution.

One with pop-off cap on top would be ideal if it was large enough. (high level chars can have absurd numbers of hit dice, so lots of room inside is needed.)

How about taking a hamster ball and gluing a flat piece of cardboard to the bottom, opposite the cap?

128
General Discussion / Re: AmeriPol thread
« on: December 17, 2019, 12:24:35 am »
Is flash player even still a thing anymore?

Last stable release was six days ago, so yes, I suppose it is.

129
General Discussion / Re: [Poi~] Poi is once again permitted (Happy thread)
« on: December 14, 2019, 03:27:18 pm »
I meant that this endless and moronic cavalcade of goalpost moving will ultimately necessitate the AI producing "Chrome opera".

The question of "true intelligence" is also just not a helpful one to ask in the first place, being more of a ready-made deepity about something that the average layperson knows is at the forefront of science. It also leads into the standard slate of AI-related philosophical questions about morality while begging the question of what "true intelligence" is, which is a handy excuse to define it in some convenient way that lets people believe themselves to be exceptionally intelligent despite a total lack of relevant education or achievements. It doesn't say anything about what the software can actually do, though, so it's firmly in the realm of questions I get from donors but not colleagues, if you take my meaning.

130
General Discussion / Re: Science Thread (and !!SCIENCE!! Thread!)
« on: December 13, 2019, 09:02:10 am »
No, Max. I think they do mean far enough. Look up near-field radiative heat transfer. It can increase radiative heat transfer orders of magnitude above what one can get from black body radiation, providing the two bodies are close enough (on the order of hundred of nanometers or less).

In a broad sense, it's similar to Förster resonance energy transfer in that regard. People try to think of photon wavelength as size, but magnitude is a closer equivalent, and the difference shows up when you start looking at how they move across very small scales.

131
General Discussion / Re: AmeriPol thread
« on: December 12, 2019, 06:35:38 pm »
Why do the R's keep harping on about the D's wanting to impeach since before Trump was even sworn into office? Are congressmen under any obligation to be unbiased going into an impeachment?
Trump was credibly accused of a multitude of crimes long before he became president, so of course some people would be eager to see him removed from office. I just don't see how that has anything to do with the current proceedings.

You know the old saw everyone's been repeating about how if neither the facts nor the law are on your side, you pound on the table? This is that.

See, you're confused in part because you're trying to find meaning in what they're saying. Decades of Fox News and years of Trump have purged the Republican base of almost anyone capable of actually listening to and understanding a complete sentence, so the Republicans need not bother making sense. They know full well that whatever they say is going to end up on Fox, where the "R" next to their name will inevitably trigger approving if inebriated hooting. Equally, they know that whatever points their opponents might make, a capital "D" on the screen will cause all sensory input to be blocked out in a fit of angry belches punctuated with racial slurs. The only reason they bother saying anything at all is to fill up airtime, get sound bites, and give their base new things to chant.

If you're wondering why the R's do anything, imagine them talking to a horde of zombies in red hats. That should make things clear.

132
General Discussion / Re: AmeriPol thread
« on: December 07, 2019, 02:26:16 pm »
And I deliberately did list MKULTRA in an attempt at steelmanning, because sometimes the tinfoil hat crowd are right. The problem is not what conspiracy theorists believe per se, but rather the methods by which they come to believe it, because those methods are not the most useful in understanding the world. In fact, they're worse than useless: they're actively toxic to having a framework for processing information that leads to believing as many demonstrably true things and as few demonstrably false things as possible.

The focus on plausibility over provability is a prime example. For one thing, the universe is provably implausible, but more importantly, your understanding of what is plausible is internal and subject to shifts in how you think. If you always think they are out to get you, that will feel more plausible to you, and you will start to see more evidence for it even if you have to bend it to fit. Moreover, other assertions with similar traits will also seem more plausible, which is how crank magnetism happens. Go far enough, and it becomes an implicit assumption that "they" planted all the contradictory evidence and hid all the proof and bought all the experts, at which point one can believe anything. It gets easier to operate in the realm of "isn't that interesting" and "what would we expect to see? exactly this" without all the fiddly checks and controls and other considerations, and it eventually soaks into your identity. Spend long enough thinking conspiratorially, and eventually all the experts have to be wrong, or else you're a fool who has wasted a ton of time on nonsense.

"Hard evidence" is great, but without a rigorous framework for defining for what it is supposed to be evidence and what other evidence would influence the probability of that theory being useful, it's just information, and can fit whatever pattern you want. "Critical thinking" is a fine idea, but without logical clarity it devolves into just casting aspersions on the credentials and motivations of anyone who disagrees with you. What our culture is evolving to do is to find ways of making reflexive, emotion-driven distrust sound smart to other people who don't know better, and conspiratorial thinking is leading the charge on that.

It sounds absurd, and I'm sure some smartass is going to put this in the quotes thread, but just because something happens to be true is not sufficient reason to believe it. Unfalsifiable things can be apparently true, as can things that aren't quite supported by the data but are concordant with it, and it's that latter that conspiracy theories evolve to run on. Believe in things only to the extent to which efforts to falsify them have returned confirmatory evidence, and then only with precision that borders on paranoia, because that's the last point at which one can stop before the slow slide into believing absolute nonsense.

133
General Discussion / Re: AmeriPol thread
« on: December 07, 2019, 12:29:44 pm »
But off-hand dismissal of all the examples I listed were not good judgment and shitty behavior, imo.

Except that they existed among a pool of countless similar theories with just as much evidence at the time. 99% of conspiracy theories hide the truth of the rest of them, if you will; just because MKULTRA existed doesn't mean Earth is flat.

By the time you've defined what it is you think is happening and why you think it's happening again with sufficient precision to discriminate it from all other theories, you're most of the way toward being able to falsify it (EDIT: or rather, meaningfully test its predictive capacity) anyway.

134
Not quite, no. Zeteticism is literally this:
That [...] data could then be used to make [...] models
There's no questions involved at all, just taking a bunch of data and building a mechanism out of it. To use your ball example, it's seeing that you can hit the ball in a certain direction with your club and deciding why that happens based solely on the congruence between your theory and the data you used to make it. Alternatively, it's seeing that the world looks flat to you and deciding that it is. That's why it is awful science: you can make any theory you want right down to "God created ad hoc physics to produce exactly these data" and have it accord with 100% of observation, so there's no predictive value.

Empiricism doesn't let you do that. You build a model (which is really just a mechanism with defined input and output parameter sets) based on theory and then identify a data set that could falsify it. Then you go do the experiments necessary to get that data and either disprove or fail to disprove the most relevant null hypothesis or equivalent. By the way, this:
 
Science is about testing observations. 
Is also wrong for this reason. We don't test observations. We test predictions.

There's also a more minor point to be made that those predictions are not always about causes. Predictions are a logical expression of a pattern, and patterns can exist  without a time component. It's totally valid to predict that if set X has Y traits it will also have Z traits because of some mechanism and go off and go look for an X that has Y but not Z or otherwise try to disprove that assertion.  Y and Z can even have spacelike separation and the process still works. Sure, there's implicitly a cause somewhere, but mechanisms need not always address it to be falsifiable.

This brings us back to Naturegirl's original suggestion, which was a neural activity-based fishing expedition. We do these all the time, especially in bioinformatics, but not to generate models (and, therefore, nothing of interest to behavioral scientists, at least in the way you've proposed) It's like GWAS in that way. The point is that, since an AI is built to classify an input set into an output set (sort of) and her original post didn't include an output set, it's not the tool to use to pull out trends. We have better tools for doing that, PCA being one of them.

The original idea was to get a whole bunch of neural data together and learn from it. That's not inherently unscientific, but there are very specific ways in which it can be a useful part of the scientific process and AI can't really help with them. What we do with a giant pile of data, be it genomic or neural or proteomic or anything else, is fish through it for correlations. You can then go look through existing models to find ones your data may be able to disprove, but you don't go hare off and propose one ex nihilo just from fishing. At most, it's a source of very specific preliminary data. Useful, but not as a deliverable.

135
Okay, wierd. There's a lot to unpack there, but let's start with the fundamentals:

What, in your own words, is zeteticism?

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