Yes, it is. Doesn't make it the
most consistent, and far from the safest.
Probably the fastest and safest would be the Eldar Webway; "safe" paths through the Warp that allow incredibly rapid transport, as in crossing entire sectors in the blink of an eye. Unless that got retconned recently, I don't pay much attention to the space elves

Ninjaedit: Worlds claimed by Chaos can sometimes be reclaimed by the Imperium, in one of their Great Crusades. The Gaunt's Ghosts series follows a regiment of Imperial Guard as they try to survive the terrors of one of those Crusades.
When Chaos launches a Black Crusade? Worlds burn. Only the extremely well-fortified (like Cadia) have a chance of fighting them off.