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[Trapezohedron]

So, first question, can multiple syndromes that grant interactions inhabit the same material?

Like let's say, hypothetically:

Vampire's Blood (blood material)
* Transforms non-dwarves into mindless blobs (syndrome 1). Dwarves are (as stated) immune to this via creature classes.
* Grants dwarves super-strength (syndrome 2). Non-dwarves are immune to this via creature classes.

[Putnam]

Yeah, this is used pretty extensively already.

More generally, syndromes that grant interactions are not special in any way except perhaps that they are not overwritten by other creature effects of the same type, and anything that can hold a syndrome can hold multiple syndromes AFAIK (haven't tested with I_EFFECTs, and it may require multiple I_EFFECTs for multiple syndromes).