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Author Topic: Untamed Virus Containment Thread: COVID-19:Mask of +1 Disease Resistance Edition  (Read 128219 times)

delphonso

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Re: Untamed Virus Containment Thread: COVID-19:Mask of +1 Disease Resistance Edition
« Reply #4350 on: September 26, 2020, 12:35:47 am »

Swing states benefit from poor virus handling as far as Trump is concerned. Day of the election, Trump supports will vote in person, Dems will vote by mail which will be thrown out.

All because the Libs are too scared of the flu SMH
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Starver

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Re: Untamed Virus Containment Thread: COVID-19:Mask of +1 Disease Resistance Edition
« Reply #4351 on: September 26, 2020, 06:44:38 am »

On UK Test'N'Trace app news, it all seem to be going Ok.

Except that it won't work on all the devices that the old (cancelled) App worked on, it isn't as accurate at proximity-tagging  as the old one, there are still many issues with booking an appointment for testing and if you tell it you have symptoms but later get an official negative test result from outside the app there's no way to tell it that and abort the isolation period timer...

Still, four million downloads and counting!
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martinuzz

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Re: Untamed Virus Containment Thread: COVID-19:Mask of +1 Disease Resistance Edition
« Reply #4352 on: September 26, 2020, 08:10:21 am »

Researchers in Amsterdam have found that the coronavirus also hits the brain hard.This can explain why people lose their sense of smell and taste, 'forget' to breathe, and also why so many patients report long term concentration loss, palpitations and memory loss.

Swollen and deformed cells.  Sticky pellets and weblike structures of defense proteins.  Tissues full of activated immune cells that died fighting..
Amsterdam researchers "were completely baffled by what they saw", when studying the brains of 21 deceased corona patients under a microscope.
The virus appears to not only cause extensive damage to the lungs, but also to the brains.

Admittedly, all patients that Paul van de Valk and his fellow researchers at the Amsterdam UMC studied had died from the corona virus.
"We don't know if we would find the same damage in patients that became less ill from the virus", says van der Valk.
But what the study does show, is that corona is much more than just a respiratory disease.
"It can almost be called a systemic disease", says van der Valk. "Just about every organ in the body is affected".

The researcher did not find many virus particles in the deceased patients.  In fact, they found none at all in the brains.
They did, however, find extensive inflammation damage.  In the lungs, obviously.  But also in the liver, the kidneys, the heart and the brains.
In nearly all patients they found extensive damage to the olfactory nerve.  This would explain the remarkable loss of smell and taste in many patients.

Striking is also the damage to a part of the brain, high in the neck, that is responisble, amongst other things, for the automatic reflex of breathing.
"We know that many patients keep walking around with too little oxygen in the blood, until they acutely get very stuffy", says van der Valk.
"it is tempting to correlate this with a damaged respiratory center in the brain".

The damage is practically everywhere. "The cerebellum, the cerebrum, everywhere we looked we found inflammatory damages",  says the pathologist.
"We were baffled and impressed by the brainf deformations we found".  For example, the team found tight clusters of 'microglial cells'  everywhere, the team writes in an article in the Lancet Microbe.  Those are antennas that regulate the immune response.
"They are super-activated, almost out of control.  In all likelyhood they made a futile last effort to stop the immune response".

The brain has it's own private immune system, that usually is tuned to very low activity, to prevent the immune system in the brain to become agitated too fast and cause damage.
Yet apparently, corona virus manages to affect and deregulate even this delicate secluded part of the immune system.
"The immunological clinical picture we see here is very rare", the researchers say.  "Yet, with Covid, we see it in nearly all patients"
This could explain the so-called 'long Covid', the phenomenon where patients that often weren't even that ill from corona report that they suffer from amnesia, headaches, extreme fatigue, and 'brain mist' for months after having recovered from the disease.

"We don't have any conclusive evidence yet, but it is quite possible that 'long covid' is caused by this", says van der Valk.
Other studies already pointed at a striking correlation between long covid and a disturbed autonomic nervous system:  patients often suffer from heart rythm disturbance and breathing disorders.

"More and more, it is starting to look like that this coronavirus mostly targets the innate immune response system, the body's frontline defense system, and makes it go haywire", says internist-immunologist Pieter van Paassen (UMC Maastricht) when asked.
"That is an important new idea, and their study supports that".

Van Paassen recently conducted a studies of 228 corona patients  (https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.120.050656).
In the worst cases he observed immune cells called neutrophiles cast a web when viewed under a microscope, exactly the same as what van der Valk's team observed in their study.
"Those cells are trying to catch the virus in their webs, but while doing that they also activate the coagulation route, which likely is the reason for the extreme blood clotting we observe in patients", says van Paassen.
"The big question is, how long does this clinical picture last", says van der Valk.
He recounts horrible stories from people that are left disabled for months.
"This could imply that, once triggered, the immune response does not know how to stop".

On the other hand, the immunological clinical picture observed has many similarities with the paralysis disease Guillain-Barré."And that disease's clinical picture does end eventually.  So there is still good hope that these effects from corona are also not going to last forever", says van der Valk.

The researchers are very curious to see what effects dexamethason, which is now a standard medicine used on corona patients in hospitals to reduce inflammatory damages, will have.  Patients are now also always treated with anti-coagulents, to prevent blood clotting.

The new finds show that this new corona virus strikes surprisingly different than other respiratory virusses, like flu and the common cold."This is some kind of hit-and-run virus", says van der Valk.  "It visits briefly, causes major damage, and then leaves the body again, leaving some patients with many additional problems caused by hyperreaction of their immune system".


Translated from  https://www.volkskrant.nl/wetenschap/coronavirus-veroorzaakt-chaos-in-de-hersenen~bac7630e/


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wierd

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Re: Untamed Virus Containment Thread: COVID-19:Mask of +1 Disease Resistance Edition
« Reply #4353 on: September 26, 2020, 08:26:45 am »

Sadly, I already knew about this. (reports of these kinds of injuries were reported all the way back in May APRIL.)

Seriously, JUST WEAR YOUR GODDAMN MASKS, AND AVOID SOCIAL CONTACT.

That is, unless you just RELISH the notion of:

Brain damage
Permanent lung damage
Multiple organ damage from inflammation responses

all because you just could not fucking live without going to the goddamn club.

This is not a little flu. Stay the fuck home.


Somebody's financial statement is not worth the quality of the remainder of your goddamn life.  Neither is the few hours of pleasure such a risky undertaking gives you.

Somebody needs to horse-whip DeSantis and Co with a motherfucking clue bat.
« Last Edit: September 26, 2020, 08:35:15 am by wierd »
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ChairmanPoo

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Re: Untamed Virus Containment Thread: COVID-19:Mask of +1 Disease Resistance Edition
« Reply #4354 on: September 26, 2020, 08:45:59 am »

Quote
Swollen and deformed cells.  Sticky pellets and weblike structures of defense proteins.  Tissues full of activated immune cells that died fighting..
Amsterdam researchers "were completely baffled by what they saw", when studying the brains of 21 deceased corona patients under a microscope.
The virus appears to not only cause extensive damage to the lungs, but also to the brains.

The obvious counterpoint is that it's far from clear this is extrapolable to milder cases, let alone asymptomatic. I'd add that it'd be interesting to compare those brains they autopsied with people who died in icu of other causes (in particular infectious causes). It might be that they're seeing the consequences of DIC in serious infections rather than covid in particular. There's been a lot of that with these case reports. A few months ago I saw some haem guy on twitter become enthusiastic about "covidcytes" in peripheral blood... which to me looked remarkably like reactive lymphocytes of the sort you see in pretty much all viral infections.

Though tbh I think noone should want to gamble with getting covid given how significant the risk is for something nasty long term  happening.
« Last Edit: September 26, 2020, 08:49:54 am by ChairmanPoo »
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wierd

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Re: Untamed Virus Containment Thread: COVID-19:Mask of +1 Disease Resistance Edition
« Reply #4355 on: September 26, 2020, 08:51:39 am »

I would say the missing feature is the lack of concern for OTHER people.

People (By and large) have a hard time accepting what a risk to their own personage entails-- In the US at least, the popular culture tends to be "He-man" like about such things. "Oh, I can handle getting a little flu!" et al.

The issue is that they do not consider how their he-man bullshit is exposing hundreds or thousands of people to social contact exposure, and killing people.

You save other people's lives, by staying away from the goddamn clubs, and avoiding social gatherings.

You don't do it for yourself; If you were doing things for yourself, you would go to the goddamn parties, clubs, and bars-- and get lit off your ass, because "Fuck those other people."  No, you stay home to protect *other people*.  You wear the mask to protect *OTHER PEOPLE*.

And of course, QED--- Americans are out whooping it up at bars like there isn't a major disease epidemic.  SMDH

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Naxza

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Re: Untamed Virus Containment Thread: COVID-19:Mask of +1 Disease Resistance Edition
« Reply #4356 on: September 26, 2020, 12:49:45 pm »

Hm, maybe this errant twitch I picked up a month or two ago is the result of asymptomatic Covid, then?

I mean, I'm assuming I still haven't caught the disease and will behave as such, but if I did, well, fuck, but also that'd mean I won't have to worry myself silly thinking something else is amiss since I can't exactly get anything checked right now, but also, organ damage, great.
« Last Edit: September 26, 2020, 01:01:25 pm by Naxza »
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hector13

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Re: Untamed Virus Containment Thread: COVID-19:Mask of +1 Disease Resistance Edition
« Reply #4357 on: September 26, 2020, 03:06:19 pm »

*confetti falls from the sky*

It was done, and in bombastic style. 2800 positive tests in one day, a new record, pushes the average number of daily positives from the last week to over 2k, and with another record 23% of tests recording positives too!

Fantastico.

I also found out the store I work at is doing Black Friday, though with the vague “not as we normally do” proviso. Hopefully that doesn’t mean BF but now with social distancing because that is not going to work.
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