It requires Mac OS X 10.12 Sierra or later. It crashes when trying to connect to 32-bit Dwarf Fortress v0.44.02. But it's the best 64-bit Mac version of Dwarf Therapist that I've ever seen, and I really appreciate it. I'm glad you are able to make this.
I'm not too concerned about it not working with 32-bit Dwarf Fortress. Having Dwarf Therapist for 64-bit Dwarf Fortress removes the only reason for running 32-bit Dwarf Fortress, imo. (I only used 32-bit Dwarf Fortress because I hadn't been able to use Dwarf Therapist with the 64-bit version of Dwarf Fortress before now.) If you really care about this issue, the included 32-bit memory layout looks fine,though, and is the same as the one that's working in the old 32-bit Dwarf Therapist build from Fricy.
It'd be kind of cool if you could make it work on Mac OS X 10.11 El Capitan. Apple raised the system requirements with Sierra, so users with older computers are stuck on El Capitan. Your Sierra+ build brings support to 66% of Mac Users. The previous High Sierra+ build from salajander only supported 37% of Mac users. So your build is a big improvement. If you somehow got it working on El Capitan, that would allow 88% of Mac users to run 64-bit Dwarf Therapist.
Thank you very much!